Case 8: Comments 7
Blood Investigations
EPP Gamma 15 (RR 6-15), Beta 9 (RR 5-10) Total Protein 84 (RR 60-75)
Highly significant for a very active immune response to Paill Spectrum infection.
Antigliaden IgG: 0.32 (RR <1.0)
Antigliaden IgA: 0.08 (RR <1.00)
The Paill Spectrum model suggests that any antigliaden antibody level greater than 20-25% of reference range as calibrated for endoscopically proven Celiac disease, is likely to have significant health effects on the patient, both directly and indirectly. Wheat antibodies (anti-gliaden antibodies) trigger low-grade malabsorption problems sufficient to affect vitamin and mineral uptake. They also affect antigen processing probably at the TAP protein level, causing the immune response to other antigens to be smoke screened by the continued presence of wheat antigen. (Also known as gliaden or gluten).
Serum Zinc 9.7 microM (RR 12.0-28.0)
The patient would benefit from having their zinc levels raised. This is a slow difficult process, complicated by poor zinc bioavailability and exacerbated by the wheat allergy / gluten intolerance.