Fibromyalgia is a widely known but little understood condition or syndrome. There are no blood tests to confirm the presence or absence of the condition. It is often diagnosed when Rheumatologists cannot confirm the presence of a classical autoimmune disorder such as SLE (Lupus) or Rheumatoid, but when there is obviously something wrong with the patient. The significance of symptoms of fibromyalgia under the Paill Spectrum model is discussed.
Fibromyalgia is a medical condition or syndrome that many doctors do not agree even exists. It is often used as a diagnosis when the doctor believes there really is something wrong with the patient, but is unable to find anything to confirm their opinion in the blood test investigations.
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The Paill Spectrum model of disease as developed by Dr. Xxxxx suggests that perhaps the most important symptom is the subjective impression of aches and pains in the upper body of the affected person, often with no or very little subjective experience of tenderness. (Tenderness is pain when you press. Sore areas can be painful but not tender, depending on what is going on).
Typically, the sore areas will respond to pain killers. However, if this is adopted as a therapy direction, doctors and patients will find over three to nine months that the dose of painkiller required to control the symptoms begins to rise. The Paill Spectrum model of disease as developed by Dr. Xxxxx suggests that a number of people are driven to accelerate their drug or painkiller usage to attempt to obtain relief from the discomfort frequently associated with the condition. Some of these people become labelled as addicts or as "addicted" to painkillers. Back To Fibromyalgia Top Others are labelled as malingerers.
There are a number of other basic symptoms which the Paill Spectrum Model of Fibromyalgia predicts, in contrast to the standard medical model of the disease:
Connective Tissue Disease, Immune or Inflammatory Screening Blood Tests in Paill Spectrum Fibromyalgia
The name Fibromyalgia is often used by Rheumatologists, when the patient has some type of soft tissue aches and pains, but all the standard screen rheumatological tests are negative.
These include tests such as:
There are a host of other tissue autoantibodies. They are often used to exclude specific diseases or tissue specific autoimmune diseases, rather than as a screen for multi-tissue autoimmune diseases. Lupus is perhaps the most common syndrome that doctors try to exclude when assessing the symptoms and signs of fibromyalgia.
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The name Fibromyalgia is often used by Rheumatologists, when the patient has some type of soft tissue aches and pains, but all the standard screen rheumatological tests are negative.
There are unfortunately a number of obvious immune vasculitic events which the average doctor is faced with. These may have no obvious disease process underlying the clinical observation of a "vasculitic" type event. These symptoms appear out of nowhere in an apparently well person, who then continues to stay well in the long term. .Back To Fibromyalgia Top
One easy relatively common and innocuous example is the finding of:
Possible mechanisms include
Tests for vasculitis usually fail to show any positive result and there is no obvious cause for the observed symptom. Doctors normally reassure their patients there is nothing wrong. Realistically, Dr. Xxxxx agrees, there does appear to be nothing wrong. :-> Back To Fibromyalgia Top
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The current medical model underlying all these conditions states that these conditions arise because the body has developed an immune response inappropriately against its own tissues. This needs to be suppressed. Indeed steroids and cytotoxic medications are often used in the treatment of fibromyalgic and autoimmune disease.
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The Paill Spectrum model implies that an appropriate immune response develops to foreign antigen either directly or where this foreign antigen attaches (as a “hapten”) to normal tissues. The model predicts that treating people with steroids or cytotoxics will suppress the immune response and result in a temporary reduction in tissue inflammation with a reduction of patient symptoms. Unfortunately, the infection continues. Most doctors, who use these types of treatments on their patients, find to their surprise that every 3 – 9 months the dose of the immune suppressive agents needs to be increased as the symptoms return. They then say that the condition must be getting worse, which it is in fact due to the immune suppression, so they need to increase the dose.
There is a natural cap on the process. Either the antigen load increases sufficiently to cause a breakthrough immune flare with germ destruction or the pain conducting nerves are exterminated by the body’s immune response with consequent reduction in patient symptoms.
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The time period over which the clinical scenario is played out is also far too long for the average doctor to remember the clinical symptoms occurring and to allow the doctor to track the progression of the disease process over time. People forget. Doctors forget too.
See hapten iso-immunisation on the CD books.
The Paill Spectrum model of disease as developed by Dr. Xxxxx, advises extreme care in introducing Paill Spectrum therapy in autoimmune conditions. For example, he has seen one patient with Myasthenia Gravis where the Paill Spectrum type therapy is causing a prolonged steady antibody titre fall in the acetyl-choline receptor antibody titres. However, it is not safe to stop the immune suppressants as the antibody titre flare which is likely to follow, will cause a marked worsening of the myasthenia symptoms.
Treatment becomes a balance of controlling the underlying Paill Spectrum infective process as well ensuring the immune process perhaps responsible for causing the acetylcholine receptor antibodies to form, is gently suppressed until the Paill Spectrum antigen load falls sufficiently to allow the immune suppressive therapy to be reduced. Back To Fibromyalgia Top
This is not meant to be an exhaustive list, merely a representative list. Back To Fibromyalgia Top
There are other symptoms mentioned in other Paill Spectrum conditions on this web site.
See Keywords Page or Syndrome Page.
The Paill Spectrum model as pioneered by Dr. Xxxxx states that Fibromyalgia and possibly some other autoimmune illnesses are caused by infection with the Paill Spectrum organism.
The presence of the organism can be detected by specific blood tests, responds to specific antibiotics, (documentable by an IgG / IgM response to those same antibiotics) and is associated with other characteristic symptoms unique to the Paill Spectrum organism. These other symptoms will also improve subtly and slowly but definitely with Paill Spectrum treatment.
Tissue pain is very difficult to eradicate with anything except maximal Paill Spectrum treatment. It also tends to recur three to nine months after cessation of antibiotic therapy. The Paill Spectrum model of disease as developed by Dr. Xxxxx relates that the Fibromyalgia group of patients has a generally poorer response to nutritional therapy than most of the Paill Spectrum groups.
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It is critical to treat people with effective therapy, not just symptomatic medication, or drugs. Medicine for “symptoms” does not change the progress of the disease.
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Cytotoxic Medications are often used. This includes medications such as:
These medications appear to give good symptomatic relief,
but in the long-term the underlying Paill Spectrum disorder will flare
over three to nine months.
Unfortunately, the modern trend is to use cytotoxic medications more and steroids less. In Dr. Xxxxx’s opinion based on the Paill Spectrum Model of disease which he has pioneered, the balance of risk or injury favours use of steroids to use of cytotoxics.
The Paill Spectrum model of disease as developed by Dr. Xxxxx, does not “blanket condemn the use of cytotoxics. It merely suggests strongly that these medications are used for specific indications to achieve specific clinical aims with definite clinical goals. Where there is an immune (or in the classical model Autoimmune) response complicating PaillSpectrum infection, these medications may in fact be beneficial to symptoms control and disease control. Where the disease process is due to Paill Spectrum, treatment may give temporary relief, but exacerbate the condition long term.
Dr. Xxxxx states that in complex circumstances
where more than one pathological process is occurring,
treatment compromises will need to be made to achieve the best outcome for the patient.
The mainstay of treatment is constant monitoring
and achieving definite clinical goals or blood test goals
before moving on to the next stage of treatment or therapy. :- l]
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What about people who are just tired, not achy or full of pains?
Disclaimer
For More Clinical Information: See :>>
CD Book Information
The CD Books are not currently available. (Planned release date is early 2008).
More information will be available on PaillSpectrum in Dr. Andrew Xxxxx’s two CD Books:
Accessing Information
Downloadable Information files (zip = pdf +mp3), are available directly through the web site.
(File on the Download Page: approximately 12MB download). :-? :-O Back To Fibromyalgia Top
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The Paill Spectrum Disease Model has been developed by Dr. Andrew Xxxxx. It will be some time before the knowledge of the syndrome becomes independently tested and accepted. Disclaimer
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